I think bedbugs are a concern for most frequent travelers these days - I certainly feel apprehensive every time I walk into a hotel room. I came across an article on Frommer's that offers good tips for preventing the little critters from infesting your home. I always pull back the sheets and check the mattress in the room, then wash everything as soon as I arrive home, but there is additional advice I hadn't thought of, like examining your luggage in the garage or bathtub, where the bugs will have a hard time climbing up the sides and will show up better against the light colored surface. Here's the link.
How to Avoid Bedbugs While Traveling
Part of the problem for me is I don't really know what I'm looking for, since I've never actually seen a bedbug. I flipped out when I found a tiny black bug on a desk at one hotel, but when I looked up bedbug photos on the internet, it didn't look anything like the pictures. It had wings for one thing, and bedbugs don't. Here are a few photos to help you identify bedbugs if you encounter them.